Expedient Synthesis of Highly Potent Antagonists of Inhibitor of Apoptosis Proteins (IAPs) with Unique Selectivity for ML-IAP
نویسندگان
چکیده
منابع مشابه
IAP Antagonists Induce Autoubiquitination of c-IAPs, NF-κB Activation, and TNFα-Dependent Apoptosis
Eugene Varfolomeev,1 John W. Blankenship,1 Sarah M. Wayson,1 Anna V. Fedorova,1 Nobuhiko Kayagaki,2 Parie Garg,2 Kerry Zobel,1 Jasmin N. Dynek,1 Linda O. Elliott,3 Heidi J.A. Wallweber,1 John A. Flygare,3 Wayne J. Fairbrother,1 Kurt Deshayes,1 Vishva M. Dixit,2,* and Domagoj Vucic1,* 1Department of Protein Engineering 2Department of Physiological Chemistry 3Department of Medicinal Chemistry Gen...
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ژورنال
عنوان ژورنال: ACS Chemical Biology
سال: 2013
ISSN: 1554-8929,1554-8937
DOI: 10.1021/cb3005512